From Sequence to Structure

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چکیده

The genomics revolution is providing gene sequences in exponentially increasing numbers. Converting this sequence information into functional information for the gene products coded by these sequences is the challenge for post-genomic biology. The first step in this process will often be the interpretation of a protein sequence in terms of the threedimensional structure into which it folds. This chapter summarizes the basic concepts that underlie the relationship between sequence and structure and provides an overview of the architecture of proteins. 1

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تاریخ انتشار 2003